Leukoreduction system (LRS) chambers are filled with blood enriched with mononuclear cells and depleted of most granulocytes and platelets. LRS chambers are an excellent starting source to obtain monocyte and lymphocyte populations, especially T cells. Cells harvested from these chambers can be directly used in many in vitro research applications.
During a routine platelet donation procedure, centrifugation separates mononuclear white blood cells from platelets, leaving the cells behind inside the LRS chamber. The cellular make-up and number of cells inside these chambers vary somewhat based on the specific collection procedure conducted. On average, these chambers have 1.7 billion mononuclear cells and <5% contaminating granulocytes. T cells can constitute up to 65% of the cells inside LRS chambers. Cells contained inside these chambers are sterile and remain viable for an extended period when stored at 2-8⁰C (>95% viable at 48 h and >90% viable at 96 h). Technical Description PDF To specify demand frequency, storage and shipping temperature, donor characteristics, additional processing, or testing needs, click on “Customize” tab.
Custom collections from a pool of thousands of healthy donors.
Flowcytometry characterization of immune cells.
Research or GMP grade positive or negative cell selection procedures.
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Controlled rate freezing using custom cryo-preservatives.
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