Cryoprecipitate is a concentrated blood component made from plasma, usually a cloudy yellow color. It contains specific proteins involved in clotting including: Fibrinogen, Factor VIII (the protein missing in patients with Hemophilia A), Factor XIII and Von Willebrand factor (helps in getting the platelets to stick together).
Slowly thawing Fresh Frozen Plasma at 1-6°C creates an environment where higher molecular weight proteins precipitate out of the plasma. Since the precipitation happens in a cold environment the resulting product is commonly called Cryoprecipitate (Cryo); however, the licensed drug name for the product is Cryoprecipitated AHF. This product name was assigned because the drug was developed to provide a high concentration of coagulation factor VIII, also known as anti-hemophilic factor, the factor deficient in Hemophilia A. Cryo is a low purity concentrate of three hemostatic proteins prepared from a single whole blood unit. A single bag of Cryo contains an average of 80 IU of factor VIII and von Willebrand factor and 150 to 250 mg of fibrinogen with some factor XIII and fibronectin. These products can also be sterilely pooled by our facility into larger doses that may be needed for patient care or research needs.
Custom collections from a pool of thousands of healthy donors.
Flowcytometry characterization of immune cells.
Research or GMP grade positive or negative cell selection procedures.
Flask or automated expansion services.
Controlled rate freezing using custom cryo-preservatives.
Monitored LN2 vapor phase storage of products and samples.